PDRN Skin Booster (Salmon DNA) : Cost, Benefits, Results & Procedure

Powerful Skin Rejuvenation & Healing Treatment

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Let’s move on from temporary fixes for tired, damaged, or dull skin. How? With PDRNs, Polydeoxyribonucleotides, the breakthrough, regenerative ingredient in skincare that works from within to make your skin youthful and radiant. Extracted from salmon sperm DNA, PDRN skin boosters are scientifically proven to work at a cellular level, repairing damage, boosting collagen, hydrating deeply, thereby reversing early signs of ageing. Read More

Why Choose Oliva Clinics For PDRN Treatment?

Here are the top reasons why you must choose Oliva Clinics for PDRNs, which are the most popular anti-ageing solutions:

Over 125 experienced MD-certified dermatologists.

V-Discover - A 5-step consultation to understand your skin, hair & body.

US-FDA approved equipment ensuring safety and effectiveness.

Achieve significant improvement in a few sessions.

No hidden costs. We ensure full transparency at every step.

Served 7,50,000+ happy clients with a 95% satisfaction rate.

What Is PDRN? (Polydeoxyribonucleotide)

PDRN or Polydeoxyribonucleotide is a compound derived from salmon DNA. It contains regenerative and anti-inflammatory properties that help in cellular repair, collagen production, and improving skin hydration and elasticity.

How Do PDRN Skin Boosters Work?

PDRN skin boosters deliver purified DNA fragments derived from salmon into the skin, triggering the body’s natural repair system. They help stimulate cell regeneration and collagen and elastin production, improving your skin’s firmness and elasticity. It also helps calm skin inflammation while refining the skin texture, significantly enhancing your skin health.

PDRN skin boosters are a great option for rejuvenating your skin, restoring balance, and speeding up the skin’s healing, making your skin more youthful.

Benefits Of PDRN Skin Booster

Reduces Wrinkles And Fine Lines

PDRNs stimulate collagen production, which helps repair cells and soften fine lines, giving you smooth, younger-looking skin.

Improves Firmness And Elasticity

They strengthen the skin’s structure from beneath, increasing its elasticity and firmness.

Enhances Hydration

The treatment helps improve the skin’s ability to retain moisture, making it supple and deeply hydrated.

Treats Uneven Skin Tone

PDRNs help regulate melanin activity and promote cell renewal, fading pigmentation and brightening skin.

Repairs Skin At A Cellular Level

The DNA fragments in the PDRNs repair the skin from deep within, rebuilding damaged skin tissue at the cellular level. This transforms your skin health from within, making it youthful.

Improves Skin Texture

The treatment reduces roughness, refines pores, and leaves your skin with a polished texture.

Calms Irritation

PDRNs reduce inflammation and stress on the skin, making them suitable for sensitive skin too.

Accelerates Wound Healing

As PDRNs promote the formation of new blood vessels and tissue regeneration, they help speed up skin recovery.

Types of PDRN Techniques Available

At Oliva, dermatologists perform PDRNs using two techniques:

  1. PDRN Injections: In this technique, the dermatologists load the syringe with the PDRN solution and inject it directly into the concern areas of the face.
  2. PDRN with M-Pen: In this technique, they create tiny micro channels in the targeted areas of the face and then infuse the PDRN solution.

NOTE:

Both techniques offer the same exceptional results, and clients can choose whichever they prefer based on their individual pain threshold.

PDRN vs Other Skin Boosters

The following table tells why PDRN is superior to other skin boosters:

Benefit PDRN (Polydeoxyribonucleotide) Other Skin Boosters
Core Action Regeneration & tissue repair at the cellular level Hydration, brightening, firming, or antioxidant protection
Key Strength Anti‑inflammatory, healing, stimulates new cell growth Enhance glow, plump skin, improve elasticity
Best For Damaged, sensitive, or ageing skin needing repair Dehydrated, dull, or sagging skin needing hydration or lift
Results Faster recovery, improved texture, long‑term regeneration Immediate radiance, smoother feel, targeted cosmetic improvement
Treatment Goal Healing + rejuvenation Enhancement + maintenance
Ideal Candidates Those with scars, post‑procedure recovery, or chronic skin issues Those seeking hydration, anti‑ageing, or antioxidant support

PDRN (Polydeoxyribonucleotide) Procedure At Oliva Clinics

Pre-Treatment

Oliva’s treatment process starts with a 5-step consultation, which gives our dermatologists a holistic understanding of your concern. It includes a trichoscan, a dermascan, body composition analysis, and a consultation with a dermatologist and a nutritionist. They identify the root cause of your concern to give you a personalised treatment plan. Addressing the root cause gives long-lasting results. Based on this analysis, the dermatologist will give you a customised treatment plan for your ageing concern. They will also recommend the number of sessions you need to achieve the best results. At this stage, you can also choose the PDRN technique you prefer: MPen or Injections, based on your comfort.

During The Treatment

For clients choosing the injection technique, the medical team will apply topical anaesthesia before the procedure. After about 45 mins, once the area becomes numb, the dermatologist will cleanse the skin, mark treatment grids, and then inject PDRN into the targeted areas.  For clients choosing the MPen, the dermatologist will mark grids on the area and then create microchannels through which they will infuse PDRN into the skin.

Post Treatment

The medical team will apply a topical cream, followed by sunscreen right after the procedure.

The following are the post-care instructions:

  • Wash your face after 6 hours, but only with filtered water.
  • Avoid makeup and exercise for 24-48 hours.
  • Don’t use any active ingredients like retinoids, AHAs, BHAs or Vitamin C for 3 days.
  • No facials, waxing, bleaching or other salon activities for at least a week.
  • Avoid scrubs, steaming, or sauna for 3 days.
  • Follow any other skincare routine your dermatologist recommends.

Expected Results & Timeline

The results of PDRN treatment vary from person to person, depending on the concern being treated and its severity. Most clients notice improved hydration and mild plumpness in the treated area right after the treatment. The fine lines begin to reduce, revealing better texture and radiance in 2-4 weeks. After 6-8 weeks, you will also notice improvement in skin elasticity and pore size.

Once you complete the required number of sessions, which is usually 5 sessions, once every 15 days, you will notice your ageing signs reducing significantly. Your skin looks more youthful, clear, and radiant.

How Much Does A PDRN Treatment Cost In India?

The cost of PDRNs starts at INR 18,000 per session. However, it varies based on the number of sessions you will need. To know the exact cost, book a consultation with us.

Frequently Asked Questions On PDRN Skin Booster

People over 18 and early signs of ageing, dullness, prominent open pores, fine lines, and photodamage can opt for PDRN treatment.

People with active infections, herpes, pustular acne, keloidal tendency, autoimmune diseases, allergic to marine collagen and seafood, and pregnant and breastfeeding women.

Yes, PDRN is anti-inflammatory, gentle, soothing, and safe across all skin types. Make sure you take the treatment from an experienced dermatologist.

You may experience mild redness or light bumps on the treated area, which will subside in a few hours. Don’t apply makeup for 48 hours after the treatment.

Yes, PDRN results are long-lasting. Dermatologists recommend maintenance sessions to maintain the results.

PRP treatment uses plasma, while PDRN uses salmon DNA – both are effective for premature ageing signs.

Yes, dermatologists often combine PDRN with other skin rejuvenation treatments, like laser toning, chemical peels, microneedling, and others to enhance PDRN results.

You may experience temporary redness, slight swelling or bruising, which subsides in a few hours.

No, PDRN is not a painful treatment as it involves numbing cream.

Reviewed by Dr. Debatri Datta
MBBS, MD in Dermatology, Venereology & Leprosy
Written by : Dr. Debatri Datta
Updated on: December 2, 2025